PReS-FINAL-2327: Abatacept in the treatment of refractory uveitis
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منابع مشابه
PReS-FINAL-2327: Abatacept in the treatment of refractory uveitis
Introduction Uveitis is one of the most serious manifestations of Juvenile Idiopathic Arthritis (JIA), with the potential to cause severe sight-threatening ocular complications. The first line treatment consists of topical and oral steroids with DMARDs therapy for more severe cases, including immunosuppressive and anti-TNFa agents. Abatacept (CTLA-4 immunoglobulin) is a soluble, fully human fus...
متن کاملPReS-FINAL-2138: Abatacept (orencia) in treatment of different types of juvenile idiopathic arthritis
Methods 30 children with JIA were treated with ABA. 23 (77%) pts had polyarticular course of JIA and 7 (23%) systemic JIA. 11 children were diagnosed with acute uveitis (totally 14 affected eyes). 28 (93%) of pts were female. All patients had high degree (III) of disease activity. Mean disease duration was 6,1 ± 3,2 yr. 29 patients previously had an inadequate response to 2 or more non-biologic...
متن کاملPReS-FINAL-2234: Successful canakunimab treatment in uveitis secondary to cryopyrin-associated periodic syndrome
Introduction Cryopyrin-associated periodic syndrome (CAPS) is a constellation of diseases with a different and varying clinical spectrum which is rarely seen in childhood. The mildest form of CAPS which is familial autoinflammatory syndrome and the most severe form which is chronic inflammatory neurologic cutaneous arthropathy (CINCA) possess a very different spectrum of clinical findings. Most...
متن کاملPReS-FINAL-2061: Abatacept in therapy of juvenile idiopathic arthritis in real clinical practice
Methods The analysis includes data of 60 patients with JIA who were getting ABA in 2010 2013. The average age of patients is 12,5 years (from 6 to 18 years). 21 (35%) patients suffered from active uveitis (2 patients had one eye affection, 19 had affection of both eyes). 10 (16%) patients were diagnosed as sJIA without current systemic features. Patients received ABA intravenously at a dosage o...
متن کاملPReS-FINAL-2266: A rare cause for childhood uveitis: TINU (tubulointerstitial nephritis and uveitis) syndrome
Methods: case report 15-year-old female admitted with 20 day duration of extreme fatigue, loss of appetite, weight loss and redness in eyes and decreased vision. Ophthalmologic examination suggested bilateral anterior uveitis and right eye anterior granulomatosis uveitis. We found mild renal insufficiency; serum urea was 76 mg/dl, creatinine level was 1,2 mg/dl both of which were elevated. The ...
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ژورنال
عنوان ژورنال: Pediatric Rheumatology
سال: 2013
ISSN: 1546-0096
DOI: 10.1186/1546-0096-11-s2-p317